Perzin K H, Livolsi V A
Cancer. 1980 Mar 1;45(5):967-72. doi: 10.1002/1097-0142(19800301)45:5<967::aid-cncr2820450522>3.0.co;2-a.
Two cases of a rare entity, acinic cell carcinomas, which apparently arose primarily from ectopic salivary gland tissue, are presented. Salivary gland ducts and acini frequently may be found incorporated within intraparotid lymph nodes and less commonly within extraglandular cervical nodes. Ectopic salivary glands may also be seen, although rarely, elsewhere in the head and neck area. The most common tumor to arise from intranodal salivary gland tissue is papillary cystadenoma lymphomatosum; however, other salivary gland-type neoplasms rarely may do so. In our cases, one tumor apparently originated primarily within a paraparotid lymph node and the other in the lateral mid- to low-neck area. Neither of our patients had a demonstrable lesion of a major or minor salivary gland; thus their tumors are presumed to have originated primarily from ectopic salivary gland tissue. The clinician and the pathologist should consider the possibility of a neoplasm arising in ectopic tissue when a salivary gland type tumor is identified away from sites where major and minor salivary glands normally are found.
本文报告了两例罕见的腺泡细胞癌病例，这些肿瘤显然主要起源于异位唾液腺组织。唾液腺导管和腺泡常可在腮腺内淋巴结中发现，较少见于腺外颈部淋巴结。异位唾液腺在头颈部其他部位也可见到，尽管很少见。起源于淋巴结内唾液腺组织的最常见肿瘤是淋巴乳头状囊腺瘤；然而，其他唾液腺型肿瘤很少起源于此。在我们的病例中，一个肿瘤显然主要起源于腮腺旁淋巴结，另一个起源于颈部中下段外侧区域。我们的两名患者均未发现大唾液腺或小唾液腺有明显病变；因此，推测他们的肿瘤主要起源于异位唾液腺组织。当在正常大、小唾液腺所在部位以外发现唾液腺型肿瘤时，临床医生和病理医生应考虑肿瘤起源于异位组织的可能性。
