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阿米卡星、红霉素和强力霉素对龟分枝杆菌和偶然分枝杆菌的活性。

Activity of amikacin, erythromycin and doxycyline against Mycobacterium chelonei and Mycobacterium fortuitum.

作者信息

Garcia-Rodriguez J A, Martin-Luengo F

出版信息

Tubercle. 1978 Dec;59(4):277-80. doi: 10.1016/0041-3879(78)90005-3.

DOI:10.1016/0041-3879(78)90005-3
PMID:726085
Abstract

The activity of amikacin, erythromycin and doxycycline was studied against 18 strains of M. fortuitum and 10 of M. chelonei. The agar dilution technique was used for the evaluation of the minimum inhibitory concentration. Between the three drugs tested, amikacin was the most active, since 66.6% of the M. fortuitum and 80% of M. chelonei strains were inhibited at 12.8 microgram/ml. It is possible that in some circumstances amikacin could be useful in the treatment of infections caused by M. fortuitum or M. chelonei.

摘要

研究了阿米卡星、红霉素和强力霉素对18株偶然分枝杆菌和10株龟分枝杆菌的活性。采用琼脂稀释技术评估最低抑菌浓度。在所测试的三种药物中,阿米卡星活性最强,因为在12.8微克/毫升时,66.6%的偶然分枝杆菌菌株和80%的龟分枝杆菌菌株受到抑制。在某些情况下,阿米卡星可能有助于治疗由偶然分枝杆菌或龟分枝杆菌引起的感染。

相似文献

1
Activity of amikacin, erythromycin and doxycyline against Mycobacterium chelonei and Mycobacterium fortuitum.阿米卡星、红霉素和强力霉素对龟分枝杆菌和偶然分枝杆菌的活性。
Tubercle. 1978 Dec;59(4):277-80. doi: 10.1016/0041-3879(78)90005-3.
2
In vitro susceptiiblity of Mycobacterium fortuitum and Mycobacterium chelonei to amikacin.偶然分枝杆菌和龟分枝杆菌对阿米卡星的体外敏感性
J Infect Dis. 1978 Mar;137(3):318-21. doi: 10.1093/infdis/137.3.318.
3
Clinical usefulness of amikacin and doxycycline in the treatment of infection due to Mycobacterium fortuitum and Mycobacterium chelonei.阿米卡星和多西环素治疗偶然分枝杆菌和龟分枝杆菌感染的临床效用。
Rev Infect Dis. 1981 Sep-Oct;3(5):1068-74. doi: 10.1093/clinids/3.5.1068.
4
Disk diffusion testing with polymyxin and amikacin for differentiation of Mycobacterium fortuitum and Mycobacterium chelonei.使用多粘菌素和阿米卡星进行纸片扩散试验以区分偶然分枝杆菌和龟分枝杆菌。
J Clin Microbiol. 1982 Dec;16(6):1003-6. doi: 10.1128/jcm.16.6.1003-1006.1982.
5
Disk diffusion testing of susceptibility of Mycobacterium fortuitum and Mycobacterium chelonei to antibacterial agents.偶然分枝杆菌和龟分枝杆菌对抗菌剂敏感性的纸片扩散试验
Antimicrob Agents Chemother. 1979 Nov;16(5):611-4. doi: 10.1128/AAC.16.5.611.
6
Antimicrobial activity of ofloxacin and other agents against mycobacterial isolates from postoperative sternotomy wounds.氧氟沙星及其他药物对胸骨切开术后伤口分枝杆菌分离株的抗菌活性。
Clin Ther. 1989 Nov-Dec;11(6):775-85.
7
Treatment of nonpulmonary infections due to Mycobacterium fortuitum and Mycobacterium chelonei on the basis of in vitro susceptibilities.基于体外药敏结果对偶然分枝杆菌和龟分枝杆菌所致非肺部感染的治疗。
J Infect Dis. 1985 Sep;152(3):500-14. doi: 10.1093/infdis/152.3.500.
8
Agar disk elution method for susceptibility testing of Mycobacterium marinum and Mycobacterium fortuitum complex to sulfonamides and antibiotics.用于海分枝杆菌和偶然分枝杆菌复合群对磺胺类药物及抗生素药敏试验的琼脂纸片洗脱法
Antimicrob Agents Chemother. 1983 Oct;24(4):486-93. doi: 10.1128/AAC.24.4.486.
9
Problems in diagnosis and therapy of Mycobacterium fortuitum infections.偶然分枝杆菌感染的诊断与治疗问题
Am Rev Respir Dis. 1978 Apr;117(4):625-30. doi: 10.1164/arrd.1978.117.4.625.
10
Mutational resistance as the mechanism of acquired drug resistance to aminoglycosides and antibacterial agents in Mycobacterium fortuitum and Mycobacterium chelonei. Evidence is based on plasmid analysis, mutational frequencies, and aminoglycoside-modifying enzyme assays.突变抗性作为偶然分枝杆菌和龟分枝杆菌对氨基糖苷类及抗菌药物获得性耐药的机制。证据基于质粒分析、突变频率和氨基糖苷类修饰酶检测。
Am Rev Respir Dis. 1985 Aug;132(2):409-16. doi: 10.1164/arrd.1985.132.2.409.

引用本文的文献

1
Antimicrobial susceptibility of five subgroups of Mycobacterium fortuitum and Mycobacterium chelonae.偶然分枝杆菌和龟分枝杆菌五个亚组的抗菌药敏性
Antimicrob Agents Chemother. 1985 Dec;28(6):807-11. doi: 10.1128/AAC.28.6.807.
2
In vitro susceptibility of Mycobacterium fortuitum and Mycobacterium chelonei to cefmetazole.偶然分枝杆菌和龟分枝杆菌对头孢美唑的体外敏感性
Antimicrob Agents Chemother. 1985 Feb;27(2):282-3. doi: 10.1128/AAC.27.2.282.
3
Disk diffusion testing of susceptibility of Mycobacterium fortuitum and Mycobacterium chelonei to antibacterial agents.
偶然分枝杆菌和龟分枝杆菌对抗菌剂敏感性的纸片扩散试验
Antimicrob Agents Chemother. 1979 Nov;16(5):611-4. doi: 10.1128/AAC.16.5.611.