Voitenko I N
Ukr Biokhim Zh (1978). 1978 Sep-Oct;50(5):618-20.
The state of carbohydrate metabolism was studied under conditions of endogenous hyperlipemia induced by triton WR-1339. The data obtained testify to the fact that administration of triton WR-1339 to experimental animals intensifies lipogenesis from carbohydrates, that is confirmed by a decrease in the glycogen amount in the liver and by an activation of the pentose-phosphate pathway of carbohydrate oxidation which is important for cells intensely synthetizing fatty acids. Thus, there is a relation between disturbances in carbohydrate metabolism and development of hyperlipemia induced by the triton.
在由曲拉通WR - 1339诱导的内源性高脂血症条件下,对碳水化合物代谢状态进行了研究。所获得的数据证明,给实验动物施用曲拉通WR - 1339会增强碳水化合物的脂肪生成,这一点通过肝脏中糖原量的减少以及对细胞强烈合成脂肪酸很重要的碳水化合物氧化戊糖磷酸途径的激活得到证实。因此,碳水化合物代谢紊乱与曲拉通诱导的高脂血症发展之间存在关联。