Faul P, Schmiedt E, Kern R
Urologe A. 1978 Nov;17(6):377-81.
The morphologic differentiation grade of cytologic smear preparations proved to be a reliable gradation measurement for the prognosis of 496 patients suffering from prostate cancer and treated with estrogen. Compared with that of other cancer patients, the life expectancy of low-differentiated and anaplastic cancer patients undergoing estrogen treatment is so poor that the rationale of using antiandrogenous treatment in this carcinoma group seems extremely questionable to us. This is why, in view of the predictable prognosis, the differentiation grade of the tumor should be considered when undertaking therapeutic measures.
细胞学涂片制备的形态学分化分级被证明是496例前列腺癌患者接受雌激素治疗预后的可靠分级指标。与其他癌症患者相比,接受雌激素治疗的低分化和间变癌症患者的预期寿命很差,以至于在这个癌组中使用抗雄激素治疗的合理性对我们来说似乎极有问题。这就是为什么,鉴于可预测的预后,在采取治疗措施时应考虑肿瘤的分化程度。