Zimmermann A, Truss F
Urologe A. 1978 Nov;17(6):391-4.
Concerning the content of DNA, there are significant differences between nuclei of cells from the adenoma and those from the carcinoma of the prostate. As it is possible to measure these differences by using flow-through cytophotometry, this method might also be capable of automatizing the cytology of this organ. In a clinical study, the results of cytologic examinations and flow-through cytophotometric tests of the prostate are compared. They are comparable in the case of benign diseases of the prostate. In carcinomas of the prostate, cytology gives more positive results than flow-through cytophotometry. An improvement of these findings seems possible through the technical amendment of the method. The number of probes that can not be interpreted are fewer with flow-through cytophotometry than with cytology.
关于DNA的含量,前列腺腺瘤细胞的细胞核与前列腺癌细胞的细胞核之间存在显著差异。由于可以使用流式细胞光度术来测量这些差异,该方法也可能使这个器官的细胞学检查实现自动化。在一项临床研究中,对前列腺细胞学检查结果和流式细胞光度测试结果进行了比较。在前列腺良性疾病的情况下,两者结果具有可比性。在前列腺癌中,细胞学检查比流式细胞光度术给出的阳性结果更多。通过对该方法进行技术改进,似乎有可能改善这些结果。与细胞学检查相比,流式细胞光度术无法解读的样本数量更少。