Deschênes M
Exp Brain Res. 1981;43(3-4):304-8. doi: 10.1007/BF00238371.
In deeply anesthetized cats the synaptic events induced in fast pyramidal tract cells (Pt cells) by ventrolateral (VL) stimulation were analyzed with intracellular recordings. In 40% of the fastest conducting Pt neurons it was found that VL stimulation induced fast depolarizing potentials (FPPs) with or without underlying excitatory postsynaptic potentials (EPSPs). These FPPs were all or non fast rising events lasting about 2 ms. They could be induced by brachium conjunctivum stimulation or they could also occur spontaneously. Those occurring spontaneously had amplitude and time course similar to those evoked by VL stimulation suggesting that they were of thalamic origin. On the basis of their amplitude and lack of collision with antidromic action potentials FPPs were neither axonal nor IS events. Passage of hyperpolarizing currents could block them in an all or none manner. It is concluded that FPPs represent electronically attenuated dendritic spikes generated in small side branches (oblique ascending dendrites) or fast Pt neurons where VL terminals most probably establish their synaptic contacts.
在深度麻醉的猫中，利用细胞内记录分析了腹外侧（VL）刺激在快速锥体束细胞（Pt细胞）中诱发的突触事件。在40%传导速度最快的Pt神经元中发现，VL刺激可诱发快速去极化电位（FPPs），伴有或不伴有潜在的兴奋性突触后电位（EPSPs）。这些FPPs都是全或无的快速上升事件，持续约2毫秒。它们可由结合臂刺激诱发，也可自发出现。自发出现的FPPs的幅度和时程与VL刺激诱发的相似，表明它们起源于丘脑。基于其幅度以及与逆向动作电位不发生碰撞，FPPs既不是轴突事件也不是中间神经元事件。超极化电流的通过能以全或无的方式阻断它们。得出的结论是，FPPs代表在小侧支（斜升树突）或快速Pt神经元中产生的电衰减树突棘，VL终末很可能在这些部位建立突触联系。
