Smirnova L I, Usacheva N T, Bulycheva E M, Sorokina N V, Chernikov M P
Vopr Pitan. 1978 Nov-Dec(6):54-9.
In simulated tests on rats of the 1st months of life set up for the purpose of educing causes accounting for a highly effective utilization of the milk proteins in the early post-natal perions subject to study were the amino acids metabolism rates. An investigation of the enzymes activity showed that a falling of the milk proteins utilization effectiveness proceeds against the background of an intensive inclusion of the catabolic route of the amino acids metabolism in the liver. The urea content in the urine correlated with a gradual inclusion of the enzymatic liver systems partaking in the urine formation. The amino acids metabolism with a ramified chain in the liver tissue of rats of the first days of life was found to stand low to a still greater degree than this was the case in adult animals. One of the causes responsible for a highly effective utilization of the milk proteins in the perinatal period may be due to an incomplete functioning of the catabolic route of the amino acids metabolism in the liver.
为了找出导致出生后早期牛奶蛋白高效利用的原因，对1月龄大鼠进行了模拟试验，研究对象是氨基酸代谢率。对酶活性的研究表明，在肝脏中氨基酸代谢分解途径大量参与的背景下，牛奶蛋白利用效率下降。尿液中的尿素含量与逐渐参与尿液形成的肝脏酶系统有关。发现出生后第一天大鼠肝脏组织中具有分支链的氨基酸代谢比成年动物的情况更低。围产期牛奶蛋白高效利用的原因之一可能是肝脏中氨基酸代谢分解途径功能不完全。
