Krivenkova E M, Treshchuk L I
Vopr Pitan. 1978 Nov-Dec(6):59-64.
The object of the investigation was to study the gonadotoxic effect of thermally oxidated fats. The experiment was set up on albino male rats given for 12 months sunflower oil oxidated during its production and comprising 1.5 and 3% of the oxidation products. A protracted consumption of thermally oxidated fats leads to a change of some functional and morphological characteristics of the spermatogenesis, e.g. to distrophic changes, a fall of the spermatogenesis index and to diminution in the number of the pathological forms of the spermatozoids, along with a reduced time of the spermatozoids mobility and their resistance to a sodium chloride solution. The functional and morphological changes are observed to occur with inclusion in the oil ration containing 1.5% of the oxidation products and these become stronger on addition of a more oxidated oil.
该研究的目的是研究热氧化脂肪的性腺毒性作用。实验以雄性白化大鼠为对象，给它们喂食在生产过程中氧化的葵花籽油，其中氧化产物含量分别为1.5%和3%，持续喂食12个月。长期食用热氧化脂肪会导致精子发生的一些功能和形态特征发生变化，例如出现营养不良性变化、精子发生指数下降、精子病理性形态数量减少，同时精子活力时间缩短以及它们对氯化钠溶液的抵抗力降低。当食用油中氧化产物含量为1.5%时，就会观察到功能和形态上的变化，而加入氧化程度更高的油时，这些变化会变得更明显。
