Naito H, Matsuzaki M, Takahashi Y, Matsuda Y, Ogawa H, Sasaki T, Kumada T, Kusukawa R, Takashiba K, Ikee Y
J Cardiogr. 1981 Mar;11(1):79-88.
Supine ergometer exercise test was performed in 10 healthy subjects and 9 patients who had severe stenosis in the left anterior descending coronary artery [5 patients with stenosis proximal to the septal perforator (proximal LAD disease) and 4 patients with stenosis distal to the septal perforator (distal LAD disease)]. In healthy subjects and patients with distal LAD disease, the increment of septal excursion (IVS Ex) and percent systolic thickening of the septum (% delta Th) during exercise returned to the pre-exercise level with a few minutes after exercise. In patients with proximal LAD disease, IVS Ex decreased to 1.4 +/- 1.2 mm during exercise form the pre-exercise level (7.4 +/- 0.7 mm) and % delta Th decreased to 6.4 +/- 5.1% during exercise from the pre-exercise level (37.2 +/- 8.4%). After exercise, IVS Ex and % delta Th increased to 8.6 +/- 0.9 mm at 2 min and 38.0 +/- 9.8% at 3 min respectively and then returned to the pre-exercise level. End-diastolic wall thickness (WTh) did not change during and after exercise in healthy subjects and patients with distal LAD disease, while in patients with proximal LAD disease, WTh increased for a few minutes after exercise and returned to the pre-exercise level. The change of electrocardiogram and symptom of angina pectoris lasted longer than the abnormal wall motion.
对10名健康受试者和9名左前降支冠状动脉严重狭窄的患者进行了仰卧式测力计运动试验[5名患者的狭窄位于间隔支穿支近端(近端左前降支病变),4名患者的狭窄位于间隔支穿支远端(远端左前降支病变)]。在健康受试者和远端左前降支病变患者中,运动期间室间隔运动幅度增加(IVS Ex)和室间隔收缩期增厚百分比(% delta Th)在运动后几分钟内恢复到运动前水平。在近端左前降支病变患者中,运动期间IVS Ex从运动前水平(7.4±0.7 mm)降至1.4±1.2 mm,% delta Th从运动前水平(37.2±8.4%)降至6.4±5.1%。运动后,IVS Ex和% delta Th分别在2分钟时增加到8.6±0.9 mm,在3分钟时增加到38.0±9.8%,然后恢复到运动前水平。在健康受试者和远端左前降支病变患者中,舒张末期壁厚(WTh)在运动期间和运动后均无变化,而在近端左前降支病变患者中,运动后WTh增加几分钟并恢复到运动前水平。心电图变化和心绞痛症状持续的时间比异常壁运动更长。