Mosdøl G, Sjaastad O V, Blom A K
J Endocrinol. 1981 Aug;90(2):159-66. doi: 10.1677/joe.0.0900159.
The concentration of oxytocin in the jugular venous plasma of goats was studied by radioimmunoassay and the intramammary pressure measured upon manual stimulation of the udder and hand-milking. Before stimulation the concentrations of oxytocin were close to the limit of detection, about 3 pg/ml. Manual stimulation of the udder resulted in a short-lasting increase in plasma oxytocin in 11 out of 18 experiments carried out on nine goats. There were large variations between and within individuals in the magnitude of the oxytocin increase. Hand-milking was in general as efficient stimulus for oxytocin release. In experiments in which manual stimulation had led to a large increase in plasma oxytocin, the ensuing hand-milking did not lead to a further increase. In three experiments neither manual stimulation of the udder not hand-milking resulted in any significant increase in plasma oxytocin. The intramammary pressure increased upon manual stimulation of the udder and/or hand-milking in four out of six experiments. There was, in general, a close time-relationship between changes in intramammary pressure and plasma oxytocin.
通过放射免疫分析法研究了山羊颈静脉血浆中催产素的浓度，并在人工刺激乳房和手工挤奶时测量了乳房内压力。在刺激前，催产素的浓度接近检测极限，约为3 pg/ml。在对9只山羊进行的18次实验中，有11次人工刺激乳房导致血浆催产素短暂升高。个体之间以及个体内部催产素升高的幅度存在很大差异。手工挤奶总体上是催产素释放的有效刺激。在人工刺激导致血浆催产素大幅升高的实验中，随后的手工挤奶并未导致进一步升高。在三次实验中，无论是人工刺激乳房还是手工挤奶，都未导致血浆催产素显著升高。在六次实验中的四次，人工刺激乳房和/或手工挤奶后乳房内压力升高。总体而言，乳房内压力变化与血浆催产素之间存在密切的时间关系。
