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儿童良性复发性第六颅神经麻痹

Benign recurrent VI nerve palsy in childhood.

作者信息

Bixenman W W, von Noorden G K

出版信息

J Pediatr Ophthalmol Strabismus. 1981 May-Jun;18(3):29-34. doi: 10.3928/0191-3913-19810501-07.

Abstract

The case of a child with six documented episodes of benign recurrent unilateral VI nerve palsy between the ages of 2 1/2 months and 3 years is presented. Despite the recognized self-limiting course of this disorder, its possible evolution into a comitant esotropia makes close follow-up mandatory. The practical aspects of management including maintenance occlusion therapy are stressed as well as the need for prompt surgical intervention once the acquired stabismus has become stabilized. The etiology of benign VI nerve palsy of childhood may have the same immunological basis as other cases of para-infectious neuropathy. This isolated postinfective cranial mononeuropathy easily blends into the continuum of neurological involvement seen with the Landry-Guillian-Barre syndrome. With recovery from the initial episode, the abducens nerve may have become predisposed to recurrent inflammatory episodes and recurrent loss of function. Most often these recurrences are triggered by febrile illnesses of childhood.

摘要

本文介绍了一名2个半月至3岁之间有6次良性复发性单侧第六颅神经麻痹记录病例。尽管该疾病公认有自限性病程,但其可能演变为共同性内斜视,因此密切随访必不可少。强调了包括维持遮盖疗法在内的管理实际方面,以及一旦获得性斜视稳定后及时进行手术干预的必要性。儿童良性第六颅神经麻痹的病因可能与其他感染后神经病病例有相同的免疫基础。这种孤立的感染后颅单神经病很容易融入Landry-Guillian-Barre综合征所见的神经受累连续过程。随着最初发作的恢复,外展神经可能已易患复发性炎症发作和反复性功能丧失。这些复发最常由儿童期发热性疾病引发。

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