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Inhibition of histidine decarboxylase by imidazole derivatives.

作者信息

Kelley J L, McLean E W, Miller C A

出版信息

J Pharm Sci. 1981 Mar;70(3):341-3. doi: 10.1002/jps.2600700334.

Abstract

A series of 4-imidazolylmethyl arylsulfides, sulfoxides, and sulfones and two carbon isosteres of 4-imidazolylmethylphenyl sulfide (I) were synthesized and tested for inhibition of histidine decarboxylase from rat stomach. None of these analogs of I met the criterion of a potent and specific inhibitor of histidine decarboxylase.

摘要

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