速尿和根皮素敏感的人红细胞被动钠钾通量的氯依赖性
Chloride dependence of frusemide- and phloretin-sensitive passive sodium and potassium fluxes in human red cells.
作者信息
Chipperfield A R
出版信息
J Physiol. 1981 Mar;312:435-44. doi: 10.1113/jphysiol.1981.sp013636.
Abstract
- In outdated human red blood cells, there was a Ko-dependent, ouabain-insensitive efflux of Na that was inhibited by frusemide and phloretin. 2. It was reduced or absent (a) in media containing Ca or Mg, (b) in fresh cells. 3. In media with Cl partly replaced by NO3, Na efflux, and its sensitivity to Ko and frusemide, were reduced. 4. The saturable component of ouabain-insensitive K influx was dependent on Cl and inhibited by frusemide and by phloretin. 5. Bromide also supported a frusemide-sensitive, ouabain-insensitive K influx but acetate and SO4 (like NO3) did not.
摘要
- 在衰老的人体红细胞中，存在一种依赖钾离子（Ko）且对哇巴因不敏感的钠离子外流，这种外流可被速尿和根皮素抑制。2. （a）在含有钙或镁的培养基中，（b）在新鲜细胞中，这种外流减少或不存在。3. 在氯离子部分被硝酸根取代的培养基中，钠离子外流及其对钾离子和速尿的敏感性降低。4. 对哇巴因不敏感的钾离子内流的可饱和成分依赖于氯离子，并被速尿和根皮素抑制。5. 溴离子也支持一种对速尿敏感、对哇巴因不敏感的钾离子内流，但醋酸根和硫酸根（如硝酸根）则不支持。
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本文引用的文献
1
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J Physiol. 1957 Apr 3;136(1):148-73. doi: 10.1113/jphysiol.1957.sp005749.
2
Sodium and potassium movements in human red cells.人体红细胞中钠和钾的运动
J Physiol. 1956 Nov 28;134(2):278-310. doi: 10.1113/jphysiol.1956.sp005643.
3
Chloride-activated passive potassium transport in human erythrocytes.人红细胞中氯离子激活的被动钾转运
Proc Natl Acad Sci U S A. 1980 Mar;77(3):1711-5. doi: 10.1073/pnas.77.3.1711.
4
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5
The behaviour of the sodium pump in red cells in the absence of external potassium.在无细胞外钾的情况下红细胞中钠泵的行为
J Physiol. 1967 Sep;192(1):159-74. doi: 10.1113/jphysiol.1967.sp008294.
6
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7
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Acta Physiol Scand. 1967 Oct-Nov;71(2):168-85. doi: 10.1111/j.1748-1716.1967.tb03723.x.
8
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10
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