Umerah B C
J Urol. 1981 Aug;126(2):164-5. doi: 10.1016/s0022-5347(17)54427-4.
I have studied 68 patients with hydronephrosis. Except when complicated by infection, calculosis, cancer and severe strictures, function at excretory urography was relatively good even in advanced cases of hydronephrosis. In Zambia, Central Africa the intensity of infection and the disordered ureteral motility are the most important factors in the pathogenesis of bilharzial hydronephrosis. In other countries strictures, calculosis, ureteroceles, vesicoureteral reflux and bladder cancer apparently are more significant in these cases. Since reimplantation of the ureters usually fails because of fibrosis conservative treatment is advocated with periodic dilation of troublesome stricture(s). This is especially true since supra-infection is rare even after repeated surgical procedures. The importance of geographical variations of the disease and the relevance to clinical management are stressed.
我研究了68例肾积水患者。除合并感染、结石、癌症及严重狭窄外,即使在晚期肾积水病例中,排泄性尿路造影时的肾功能相对良好。在中非的赞比亚,感染强度和输尿管动力紊乱是血吸虫性肾积水发病机制中最重要的因素。在其他国家,狭窄、结石、输尿管囊肿、膀胱输尿管反流和膀胱癌在这些病例中显然更为重要。由于输尿管再植术通常因纤维化而失败,因此主张采用保守治疗,定期扩张引起麻烦的狭窄部位。尤其如此,因为即使经过多次手术,上行感染也很少见。强调了该疾病地理差异的重要性及其与临床管理的相关性。