Bertram G, Winkelmann W, Wilcke O, Rose K G
Laryngol Rhinol Otol (Stuttg). 1981 Jun;60(6):308-11.
The radio-immuno-assay of the pituitary hormone prolactin represents the basis for a functional differentiation of the so-called chromophobic adenomas. Two thirds of these tumors produce this hormone. For a long period of growth these adenomas are localized in the middle of the sella turcica. Their first direction of growth is towards the sinus sphenoidalis. At the ENT-clinic of the Cologne University two prolactin producing adenomas have been detected as the cause of suspected changes of the sinus sphenoidalis. The need for an endocrinological diagnosis in cases of unknown processes of the sinus sphenoidalis, the indication for surgery, and the medicamental treatment of these tumors with 2-Br-alpha-Ergocriptine (Parlodel) is discussed.
垂体激素催乳素的放射免疫测定是所谓嫌色性腺瘤功能分化的基础。这些肿瘤中有三分之二会产生这种激素。在很长一段时间的生长过程中，这些腺瘤位于蝶鞍中部。它们最初的生长方向是朝向蝶窦。在科隆大学的耳鼻喉科诊所，已检测出两例产生催乳素的腺瘤是蝶窦疑似病变的病因。本文讨论了在蝶窦出现不明病变时进行内分泌诊断的必要性、手术指征以及用2-溴-α-麦角隐亭（ Parlodel）对这些肿瘤进行药物治疗的情况。
