Gitsch E, Philipp K
Oncology. 1981;38(5):265-8. doi: 10.1159/000225567.
The introduction, in 1969, of radionuclide-assisted radical surgery using colloidal gold resulted in a substantial reduction of mortality from relapses with nodal involvement. While Wertheim's operation practiced between 1961 and 1965 was associated 50% recurrence mortality, mortality for all clinically operable stages dropped to 43.5% between 1966 and 1973, stage Ib mortality decreasing from 47.4% (1961-1965) to 26.9% (1966-1973). Within technetium labeling, which was introduced in 1977, the nodectomy potential was increased from an original 52.5% obtained with 198 colloidal gold and a scanner or eye probe to 88% obtained with the camera technique and technetium in 1979.
1969年采用胶体金进行放射性核素辅助根治性手术，使伴有淋巴结受累的复发死亡率大幅降低。1961年至1965年间施行的韦特海姆手术复发死亡率为50%，而1966年至1973年间所有临床可手术阶段的死亡率降至43.5%，Ib期死亡率从1961 - 1965年的47.4%降至1966 - 1973年的26.9%。在1977年引入的锝标记技术中，淋巴结切除术的成功率从最初使用198胶体金和扫描仪或眼探头时的52.5%提高到1979年使用相机技术和锝时的88%。
