[多发性硬化症中的构音障碍和共济失调阵发性发作]

[Paroxysmal attacks of dysarthria and ataxia in multiple sclerosis].

作者信息

Zavalishin I A, Nevskaia O M, Niiazbekova A S

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(11):1645-9.

Abstract

A description of 2 cases of disseminated sclerosis during exacerbations and paroxysms of dysarthria and ataxia in the clinical picture is given. These attacks are connected with processes of demyelinization and are differentiated with epilepsy. On the basis of neurophysiological studies the mechanisms of paroxysmal dysarthria and ataxia are discussed. The attacks were arrested under the influence of carbamazepine. The action of the drug is explained by its manifold properties.

摘要

本文描述了2例播散性硬化症患者，临床表现为构音障碍和共济失调的加重与发作。这些发作与脱髓鞘过程有关，可与癫痫相鉴别。基于神经生理学研究，探讨了发作性构音障碍和共济失调的机制。在卡马西平的影响下，发作得到了控制。该药物的作用可由其多种特性来解释。