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[患有缺氧和败血症的早产儿的脑组织学]

[Brain histology of premature infants who have suffered hypoxia and sepsis].

作者信息

Zhukova T P, Muchaidze Iu A, Afonina L G

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(12):1788-94.

PMID:726772
Abstract

Results of brain studies in 38 premature infants with severe peri- and postnatal pathology (intracranial labor trauma, asphyxia, sepsis) are presented. Clinico-morphological data detected that profound prematurity and consequently a profound immaturity of the brain, complicated by hypoxic damages during labor and early developing septic infections, lead to an expressed retardation and irreversible degenerative changes, especially in the brain structures which develop later. From the neurological point of view the most serious in relation to the prognosis are those children who are in a state of a stable inhibition of the CNS.

摘要

本文呈现了对38名患有严重围产期和产后病理状况(颅内产伤、窒息、败血症)的早产儿的脑部研究结果。临床形态学数据表明,极度早产以及随之而来的大脑极度不成熟,再加上分娩期间的缺氧损伤和早期发生的败血症感染,会导致明显的发育迟缓以及不可逆的退行性变化,尤其是在较晚发育的脑结构中。从神经学角度来看,对于预后而言最严重的是那些处于中枢神经系统稳定抑制状态的儿童。

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