Couselo Sánchez J M, Méndez Rodríguez I, Fuster Siebert M, Castro Gago M, Monasterio Corral L, Iglesias Diz L
Rev Esp Oncol. 1980;27(4):571-8.
A check is made of the hematologic disorders in 20 children with neuroblastoma and its relation with the stage of the tumour. The 75% of the patients had metastasis when they are examined, 70% anemia, 15% leukopenia, 20% thrombopenia and 50% leukoerythroblastosis. The patients with leukoerythroblastosis all had remote metastasis and made up 66% of the children with IV or IV-S stage. In 50% of the patients there was metastasis in the bone marrow and 80% of these had leukoerythroblastosis.
对20例神经母细胞瘤患儿的血液系统疾病及其与肿瘤分期的关系进行了检查。75%的患者在检查时已有转移,70%有贫血,15%有白细胞减少,20%有血小板减少,50%有幼粒-幼红细胞增多。有幼粒-幼红细胞增多的患者均有远处转移,占IV期或IV-S期患儿的66%。50%的患者骨髓有转移,其中80%有幼粒-幼红细胞增多。