Soyka P, Zellweger G
Schweiz Med Wochenschr. 1981 Jun 27;111(26):1007-10.
Analysis of causes of death in 54 patients in the Zürich Burn Center has shown that pneumonia and septicemia occur secondary to pulmonary edema. Pulmonary infection and septicemia were the main causes of death in our cases. Pathophysiologically, a timetable of danger phases can be established: a) 1st day: death from unknown cause (organ edemas); b) 2nd to 6th day: pneumonia and pulmonary edema in combinations of varying degrees; c) after the 6th day: death from pneumonia and septicemia. Wound infection alone seldom causes septic death. From this it is concluded that the badly burned patient should not be overhydrated in the initial phase of therapy. Kidneys can be subjected to more strain than was previously supposed.
对苏黎世烧伤中心54例患者的死因分析表明，肺炎和败血症继发于肺水肿。肺部感染和败血症是我们病例中的主要死因。从病理生理学角度，可以制定一个危险阶段时间表：a）第1天：死因不明（器官水肿）；b）第2至6天：不同程度组合的肺炎和肺水肿；c）第6天之后：死于肺炎和败血症。单纯伤口感染很少导致败血症死亡。由此得出结论，在治疗的初始阶段，严重烧伤患者不应过度补液。肾脏承受的压力可能比之前认为的更大。
