Angelov A, Vicheva S
Vutr Boles. 1981;20(3):8-14.
Two patients were described that died of gastric carcinoma, the first clinical manifestations of the disease being a hemorrhagic diathesis. The morphological examination revealed multiple tumour emboli in microcirculation of bone morrow and internal organs, that led to the development of disseminated intravasal coagulation with consumptive coagulopathy. Megacarycytosis was observed in bone marrow and spleen as well as megacaryocytemia in lungs as a manifestation of compensatory reaction.
描述了两名死于胃癌的患者,该疾病的最初临床表现为出血素质。形态学检查发现骨髓和内脏微循环中有多个肿瘤栓子,导致弥散性血管内凝血伴消耗性凝血病的发生。在骨髓和脾脏中观察到巨核细胞增多,在肺中观察到巨核细胞血症,这是一种代偿反应的表现。