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[丰富环境对生长中大鼠大脑皮质功能和生化指标的影响]

[Effect of an enriched environment on the functional and biochemical indices of the cerebral cortex of growing rats].

作者信息

Sitkin M I

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1981;31(2):387-94.

PMID:7269789
Abstract

Experiment was aimed at studying the influence of conditions in which developing rats are kept, on conditioned behaviour, and functional and biochemical activities of the cerebral cortex. It was shown that a two-month stay of the animals (beginning with the 15th day of their life) in enriched play surroundings accelerates differential conditioning and causes an enhancement of the limit and index of photic driving on EEG, as well as biochemical shifts (enhanced activity of lactate dehydrogenase and of its isoenzymes, an increase of the content of sulfhydryl groups) in the cerebral cortex.

摘要

实验旨在研究发育中的大鼠所处环境对其条件行为以及大脑皮质功能和生化活动的影响。结果表明,动物(从出生第15天开始)在丰富的游戏环境中饲养两个月,可加速分化型条件反射的形成,并使脑电图上光驱动的极限值和指标增强,同时大脑皮质出现生化变化(乳酸脱氢酶及其同工酶活性增强,巯基含量增加)。

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