Pattern recognition and time-dependent QSAR applied to morphinomimetic opioids.
作者信息
Mager P P
出版信息
Act Nerv Super (Praha). 1981 Jun;23(2):136-56.
PMID:7270022
Abstract
Pattern recognition and multivariate time-dependent structure-activity relationships were applied to a series of N-4-substituted 1-(2-arylethyl)-4-piperidinyl-N-phenylpropanamides. A correct classification of drugs to similar clusters requires identical results obtained from biological and chemical pattern recognition. The time point of the bioassay determines the significance of physicochemical features, and it was shown that substituent contributions vary within the time of bioassay.
摘要
相似文献
1
Pattern recognition and time-dependent QSAR applied to morphinomimetic opioids.
Act Nerv Super (Praha). 1981 Jun;23(2):136-56.
2
[The use of pattern recognition for analysing the possible relation between molecular structure of polycyclic hydrocarbons and their carcinogenicity].[利用模式识别分析多环芳烃分子结构与其致癌性之间的可能关系]
C R Seances Acad Sci III. 1981 Feb 16;292(7):495-8.
3
Proceedings: Pattern recognition.
Cancer Chemother Rep 2. 1974 Dec;4(4):43.
4
A statistical pattern recognition approach for determining cellular viability and lineage phenotype in cultured cells and murine bone marrow.一种用于确定培养细胞和小鼠骨髓中细胞活力及谱系表型的统计模式识别方法。
Cytometry A. 2007 Aug;71(8):612-24. doi: 10.1002/cyto.a.20416.
5
Parabolic quantitative structure-activity relationships and photodynamic therapy: application of a three-compartment model with clearance to the in vivo quantitative structure-activity relationships of a congeneric series of pyropheophorbide derivatives used as photosensitizers for photodynamic therapy.
Photochem Photobiol. 1999 Nov;70(5):781-8.
6
[Pharmaceutical chemistry of neuroleptic drugs].
Acta Pharm Hung. 2005;75(1):37-53.
7
Computerized pattern recognition: a new technique for the analysis of chemical communication.计算机模式识别：一种化学通讯分析的新技术。
Science. 1985 Apr 12;228(4696):175-7. doi: 10.1126/science.3975636.
8
Pattern recognition in capillary electrophoresis data using dynamic programming in the wavelet domain.小波域中基于动态规划的毛细管电泳数据模式识别
Electrophoresis. 2008 Jul;29(13):2828-40. doi: 10.1002/elps.200700831.
9
10
Synthesis of some N-substituted 3,4-pyrroledicarboximides as potential CNS depressive agents.
Pharmazie. 2000 Jan;55(1):9-16.
Zotero 插件