Chalupa W
Adv Exp Med Biol. 1978;105:473-95. doi: 10.1007/978-1-4684-3366-1_25.
Ruminants obtain amino acids (AA) from microbial protein synthesized in the rumen and from feed proteins that escape ruminal degradation. Synthesis of microbial protein provides a mechanism for obtaining AA from NPN. Effectiveness of NPN utilization depends upon production and utilization of ammonia by rumen microbes. Because ammonia is produced from protein and NPN, feeding proteins resistant to microbial degradation forces utilization of ammonia derived from NPN. The quantity of microbial cells formed in the anaerobic rumen fermentation system is primarily dependnt upon energy supply but can be modulated by types and supplies of other nutrients (i.e. amino-N, minerals growth factors) and by growth rate of rumen bacteria. Potential quantities of NPN that can be utilized with different feed ingredients can be estimated from amounts of feed protein degraded in the rumen, and requiring transformation into protein via growth of rumen microbes, and from amounts of energy provided by feed ingredients. High energy feed ingredients with low amounts of degradable protein are most favorable for NPN utilization, but NPN has also been used successfully with high-fibrous, low energy feed materials. Growth, lactation and reproduction have been obtained on diets containing more than 97% of the nitrogen from NPN, but microbial protein alone cannot provide quantities of AA needed for high levels of productivity. Regulating ruminal degradation of dietary protein and utilizing NPN for rumen protein production is a highly desirable strategy for producing human foods with ruminants.
反刍动物从瘤胃中合成的微生物蛋白以及未被瘤胃降解的饲料蛋白中获取氨基酸(AA)。微生物蛋白的合成提供了一种从非蛋白氮(NPN)获取氨基酸的机制。NPN利用的有效性取决于瘤胃微生物对氨的产生和利用。由于氨由蛋白质和NPN产生,饲喂抗微生物降解的蛋白质会促使利用来自NPN的氨。在厌氧瘤胃发酵系统中形成的微生物细胞数量主要取决于能量供应,但可受其他营养物质(即氨基氮、矿物质生长因子)的类型和供应以及瘤胃细菌生长速率的调节。可根据瘤胃中降解的饲料蛋白量以及需要通过瘤胃微生物生长转化为蛋白质的量,以及饲料成分提供的能量来估计可与不同饲料成分一起利用的NPN的潜在量。可降解蛋白含量低的高能量饲料成分最有利于NPN的利用,但NPN也已成功用于高纤维、低能量的饲料原料。在含氮量超过97%来自NPN的日粮上已实现生长、泌乳和繁殖,但仅靠微生物蛋白无法提供高水平生产所需的氨基酸量。调节日粮蛋白质的瘤胃降解并利用NPN进行瘤胃蛋白质生产是利用反刍动物生产人类食物的一种非常理想的策略。