Harper R G, Greenberg M, Farahani G, Glassman I, Kierney C M
Am J Obstet Gynecol. 1981 Sep 1;141(1):39-42. doi: 10.1016/0002-9378(81)90672-4.
Fetal movements, fetal heart rate patterns, and serum estriol levels were prospectively monitored in 91 high-risk and normal pregnant women. In four women, there was cessation of fetal movements. In three of these cases, there were pathologic changes in fetal heart rate patterns, with one neonatal death. Of the 87 women who did not demonstrate cessation of fetal movements, one had changes in fetal heart rate patterns. The difference between the two groups was statistically significant (Z test: p less than 0.001). No correlation was found between fetal movements and serum estriol levels in this study. Daily recording of fetal movements can be used as an effective screening test, with high sensitivity and specificity for the fetus in utero. Cessation of fetal movement places the fetus in a high-risk category and should alert the physician to the need for non-stress tests.
对91名高危和正常孕妇进行了前瞻性的胎动、胎心率模式及血清雌三醇水平监测。4名孕妇出现胎动停止。其中3例伴有胎心率模式的病理改变，1例新生儿死亡。在87名未出现胎动停止的孕妇中，1例有胎心率模式改变。两组之间的差异具有统计学意义（Z检验：p<0.001）。本研究未发现胎动与血清雌三醇水平之间存在相关性。每日记录胎动可作为一种有效的筛查试验，对宫内胎儿具有高敏感性和特异性。胎动停止使胎儿处于高危类别，应提醒医生有必要进行无应激试验。
