Burke J S, Colby T V
Am J Surg Pathol. 1981 Jun;5(4):343-52.
Thirty-three biopsies showing dermatopathic lymphadenopathy were obtained from patients with documented cutaneous mycosis fungoides and were studied together with an equal number of dermatopathic lymph nodes derived from patients without evidence of mycosis fungoides. The nodes were evaluated for a variety of histologic features including mitotic figures, immunoblasts, and in particular for the number of atypical cerebriform lymphocytes. Atypical lymphocytes were found to be equally as frequent among both groups of dermatopathic lymph nodes without any statistically significant differences in quantitation or distribution. Similarly, no other morphologic variable was found which would allow an objective distinction of dermatopathic lymphadenopathy from patients with or without mycosis fungoides.
从患有皮肤蕈样霉菌病的患者身上获取了33份显示皮肤淋巴细胞浸润症的活检样本,并与同样数量的来自无蕈样霉菌病证据患者的皮肤淋巴细胞浸润症淋巴结一起进行研究。对这些淋巴结进行了多种组织学特征评估,包括有丝分裂象、免疫母细胞,特别是非典型脑回状淋巴细胞的数量。发现在两组皮肤淋巴细胞浸润症淋巴结中,非典型淋巴细胞的出现频率相同,在数量或分布上没有任何统计学上的显著差异。同样,未发现其他形态学变量能够客观地区分有或无蕈样霉菌病患者的皮肤淋巴细胞浸润症。