Kalinkov D, Kalinkov-Koehl S
Anaesthesist. 1981 Jul;30(7):347-9.
Apparative hyperventilation before intubation brings about a favourable blood gas situation, but also a bicarbonate shortage, causing metabolic acidosis with increase of blood lactate and pyruvate. In obstetrics a mother-fetus infusion of lactate can occur, which can produce fetal distress. Because of the relative immaturity of the enzyme systems in the newborn, degradation of the infused lactate proceeds very slowly. These children recover only gradually over a period of several hours. For this reason it appears advisable to hyperventilate only briefly before a quick obstetrical intubation.
插管前进行的表面过度通气会带来良好的血气状况,但也会导致碳酸氢盐缺乏,引起代谢性酸中毒,同时血乳酸和丙酮酸增加。在产科,可能会发生母胎乳酸输注,这可能导致胎儿窘迫。由于新生儿酶系统相对不成熟,输注的乳酸降解非常缓慢。这些患儿需要数小时才能逐渐恢复。因此,在快速产科插管前仅进行短暂的过度通气似乎是可取的。