Pinaud M, Raynal C, Michel P, Mineur F, Souron R
Anesth Analg (Paris). 1981;38(5-6):217-20.
Thirty-one patients undergoing neuro-radiological investigations were anesthetized by methohexital-fentanyl association. Induction of anesthesia was performed by I. V. bolus of these two agents. Anesthesia was maintained by a constant rate perfusion of methohexital and fentanyl, prepared according to body weight. Posology can be reduced hourly by modifying the perfusion rate. First hour: methohexital 2 mg/kg/hour fentanyl 5 microgram/kg/hour; second hour: methohexital 0.4 mg/kg/hour, fentanyl 2 microgram/kg/hour; third hour: methohexital 0,4 mg/kg/hour, fentanyl 1 microgram/kg/hour. If necessary this dosage was modified according to isolate reactions and thus total real consumption was 25 to 30 p. cent higher to estimated theoretical requirements. This protocol of anesthesia with controlled ventilation was well cardiocirculatory tolerated and adapted to these radiological investigations.
31例接受神经放射学检查的患者采用美索比妥-芬太尼联合麻醉。通过静脉推注这两种药物进行麻醉诱导。麻醉通过根据体重配制的美索比妥和芬太尼恒速灌注维持。每小时可通过调整灌注速率来降低剂量。第一小时：美索比妥2毫克/千克/小时，芬太尼5微克/千克/小时；第二小时：美索比妥0.4毫克/千克/小时，芬太尼2微克/千克/小时；第三小时：美索比妥0.4毫克/千克/小时，芬太尼1微克/千克/小时。如有必要，根据个体反应调整此剂量，因此实际总消耗量比估计的理论需求量高25%至30%。这种控制通气的麻醉方案具有良好的心血管耐受性，适用于这些放射学检查。
