Horton G M, Stockdale P H
Am J Vet Res. 1981 Mar;42(3):433-6.
Early weaned male crossbred lambs (n = 90) with an average weight of 14 kg were used in 6 groups to evaluate the efficacy of monensin (22 mg/g of feed) and lasalocid (12.5, 25, 50, and 100 mg/kg of feed) on naturally occurring coccidiosis. Average 24-hour oocyst output at the start of the experiment ranged from 5.7 x 10(6) to 156.7 x 10(6) for monensin-treated and 100-mg lasalocid-treated groups, respectively. Monensin and lasalocid were effective against Eimeria ninakohlyakimovae of E ahsata. To day 103, body weight gains were similar for the 4 groups fed lasalocid (336 g/day) and averaged 6% higher (P greater than 0.05) than did gains in control and monensin-treated lambs. Feed efficacy averaged 9% higher (P less than 0.05) for lambs fed 25, 50, and 100 mg of lasalocid/kg of feed and 7% higher (P greater than 0.05) for lambs fed monensin and 12.5 mg of lasalocid/kg of feed. There were no treatment effects on digestibility, although lasalocid tended to increase (P greater than 0.05) crude protein digestibility (values were higher on day 76 than on day 28). Lasalocid and monensin were potent manipulators of rumen fermentation. Increasing the amount of lasalocid in the feed was associated with successive increases (P less than 0.05) in molar proportions of propionic acid and decreases (P less than 0.05) in acetic acid. Lasalocid and monensin controlled naturally occurring coccidiosis and improved performance in early weaned lambs (45 days old) under feedlot conditions.
选用平均体重14千克的早期断奶杂交公羔羊(n = 90),分为6组,以评估莫能菌素(22毫克/克饲料)和拉沙洛西钠(12.5、25、50和100毫克/千克饲料)对自然发生的球虫病的疗效。在实验开始时,莫能菌素处理组和100毫克拉沙洛西钠处理组的平均24小时卵囊排出量分别为5.7×10⁶至156.7×10⁶。莫能菌素和拉沙洛西钠对纳氏艾美耳球虫和阿氏艾美耳球虫有效。到第103天,饲喂拉沙洛西钠的4组羔羊体重增加相似(336克/天),平均比对照组和莫能菌素处理组的羔羊高6%(P>0.05)。饲喂25、50和100毫克拉沙洛西钠/千克饲料的羔羊饲料效率平均高9%(P<0.05),饲喂莫能菌素和12.5毫克拉沙洛西钠/千克饲料的羔羊饲料效率高7%(P>0.05)。尽管拉沙洛西钠倾向于提高(P>0.05)粗蛋白消化率(76天的值高于28天),但各处理对消化率没有影响。拉沙洛西钠和莫能菌素是瘤胃发酵的有效调节剂。饲料中拉沙洛西钠含量增加与丙酸摩尔比例连续增加(P<0.05)和乙酸比例降低(P<0.05)有关。拉沙洛西钠和莫能菌素可控制自然发生的球虫病,并改善育肥条件下早期断奶羔羊(45日龄)的生产性能。