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[口服聚氯乙烯毒性的实验研究]

[Experimental research on the toxicity of PVC administered orally].

作者信息

Faa G, Dessy E, Bucarelli A, Frau G, Zucca G, Draetta G

出版信息

Boll Soc Ital Biol Sper. 1981 Apr 30;57(8):926-8.

PMID:7272069
Abstract

The AA. report the results of two experiments carried out on 24 rats Wistar treated with PVC dust ingestion. A group received 1 g of PVC dust in distilled water for only 15 days; the second group received PVC dust mixed with standard food almost 5 months till to 15 months. Pathological findings consist in marked hyperplasia of gastro-enteric mucosa, with polipoidfigures, and in a marked activation of pulmonary linforeticular tissue with cellular atipias. In one case a subcutaneous histiocytic lymphoma was observed.

摘要

作者报告了对24只经口摄入聚氯乙烯粉尘处理的Wistar大鼠进行的两项实验结果。一组仅在15天内接受了1克溶于蒸馏水的聚氯乙烯粉尘;第二组在近5个月至15个月内接受了与标准食物混合的聚氯乙烯粉尘。病理结果包括胃肠黏膜明显增生,伴有息肉样形态,以及肺淋巴网状组织明显激活并伴有细胞异型性。在一例中观察到皮下组织细胞淋巴瘤。

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