Wormser G P, Bottone E J, Tudy J, Hirschman S Z
Am J Med Sci. 1978 Jul-Aug;276(1):117-26.
The clinical spectrum of disease caused by Cardiobacterium hominis, a small, gram-negative coccobacillus, is little known to physicians. From analysis of a new case of C hominis endocarditis on a fascia lata aortic valve, and from review of all previous reports of infection due to this microorganism, a remarkably consistent clinical picture emerged. C hominis only causes endocarditis, affects middle-aged individuals with structurally abnormal, left-sided cardiac valves, and follows a subacute course associated with the frequent occurrence of mycotic aneurysms and embolic phenomena. The methodology and therapeutic importance of identifying this organism and separating it from the closely related Actinobacillus actinomycetemcomitans, Eikenella corrodens, and Haemophilus aphrophilus is emphasized. Either penicillin alone or penicillin plus an aminoglycoside is recommended for therapy.
人心杆菌是一种革兰氏阴性短小球杆菌，其所致疾病的临床谱鲜为医生所知。通过分析一例发生在阔筋膜张肌主动脉瓣的人心内膜炎新病例，并回顾此前所有关于该微生物感染的报告，得出了一幅显著一致的临床图景。人心杆菌仅引起心内膜炎，累及有结构异常的左侧心脏瓣膜的中年个体，病程呈亚急性，常伴有霉菌性动脉瘤和栓塞现象。强调了鉴定该菌并将其与密切相关的伴放线放线杆菌、腐蚀埃肯菌和嗜沫嗜血杆菌相区分的方法及治疗意义。推荐单独使用青霉素或青霉素加一种氨基糖苷类药物进行治疗。
