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一种用于记录自由活动慢性大鼠肠道蠕动的微型传感器。

A miniature transducer for recording intestinal motility in unrestrained chronic rats.

作者信息

Pascaud X B, Genton M J, Bass P

出版信息

Am J Physiol. 1978 Nov;235(5):E532-8. doi: 10.1152/ajpendo.1978.235.5.E532.

Abstract

An extraluminal strain gage force transducer has been developed for recording gastrointestinal motility in small animals such as rats. Two commercial strain gages are bonded and wires attached to form half a Wheatstone bridge. The device is placed between silicone sheeting and prepared for implantation. As many as six implanted transducers can record simultaneously contractions and tone variations of circular or longitudinal gastrointestinal muscles. The transducers have been implanted in more than 20 rats, with some units lasting up to 4 mo. Furthermore, good relationships exist between intraluminal pressure waves registered by a small intraluminal balloon and gut contractions registered by the transducer. The transducers are a useful and accurate tool for rodent gut motility studies.

摘要

已开发出一种用于记录大鼠等小动物胃肠动力的管外应变片式力传感器。将两个商用应变片粘贴并连接导线以形成半惠斯通电桥。该装置置于硅树脂片之间并准备植入。多达六个植入式传感器可同时记录胃肠环形或纵形肌肉的收缩和张力变化。这些传感器已植入20多只大鼠体内,有些装置可持续长达4个月。此外,由小型腔内气囊记录的腔内压力波与由传感器记录的肠道收缩之间存在良好的相关性。这些传感器是用于啮齿动物肠道动力研究的一种有用且准确的工具。

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