A new mouse mutant showing cerebellar abnormalities.
作者信息
Webster W S, Briggs D
出版信息
Brain Res. 1981 Aug 10;218(1-2):412-6.
PMID:7272745
Abstract
This paper describes a previously unreported recessive mutation in mice which, in the homozygous state, caused an abnormal posture, characterised by extension and abduction of the limbs on one side. This position alternated causing the mice to fall to one side or the other. The only histological abnormality noted, in the slightly smaller brains of the mutants, was a displacement and disarrangement of the Purkinje cells into the granular layer, in parts of the nodulus.
摘要
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A new mouse mutant showing cerebellar abnormalities.
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