将鸡胚暴露于氚标记的胸腺嘧啶核苷后，背根神经节中标记的退化细胞迅速出现。

Rapid appearance of labeled degenerating cells in the dorsal root ganglia after exposure of chick embryos to tritiated thymidine.

作者信息

Carr V M, Simpson S B

出版信息

Brain Res. 1981 Aug;254(1):157-62. doi: 10.1016/0165-3806(81)90066-3.

Abstract

The interval between [3H]thymidine delivery and onset of cellular degeneration in 5.5 day embryonic chick brachial dorsal root ganglia was examined autoradiographically. Of the degenerating cells, 14% were labeled by 2 h after [3H]thymidine delivery. This percentage increased for 24 h. Wing bud amputation had no effect on this percentage through 9 h. Thus, some cause of cell death other than faulty peripheral connections may exist in at least some degenerating ganglionic cells.

摘要

采用放射自显影法检测了5.5日龄鸡胚臂部背根神经节中[3H]胸腺嘧啶核苷注入与细胞变性开始之间的时间间隔。在变性细胞中，[3H]胸腺嘧啶核苷注入后2小时，14%的细胞被标记。该百分比在24小时内持续增加。在9小时内，翼芽截肢对这一百分比没有影响。因此，至少在一些变性的神经节细胞中，可能存在除外周连接缺陷以外的其他细胞死亡原因。