• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用卢戈氏坚牢蓝MBS进行髓鞘的定量组织化学分析。

Quantitative histochemistry of myelin using Luxol Fast Blue MBS.

作者信息

Scholtz C L

出版信息

Histochem J. 1977 Nov;9(6):759-65. doi: 10.1007/BF01003070.

DOI:10.1007/BF01003070
PMID:72743
Abstract

The amount of Luxol Fast Blue MBS in the band of Genarri was measured with two types of scanning microdensitometer and the optical density determined. The amount of stain measured was proportional to the section thickness employed, thus demonstrating that the dye has stoichiometric properties in tissue sections. Blocks of tissue treated with phospholipid solvents showed an increased uptake of stain, suggesting that phospholipids are not a primary substrate for the dye in myelin staining. The dye may, therefore, be used to quantify myelin in tissue sections.

摘要

使用两种类型的扫描显微密度计测量了Genarri带中Luxol固蓝MBS的含量,并测定了光密度。所测量的染色量与所采用的切片厚度成正比,从而表明该染料在组织切片中具有化学计量特性。用磷脂溶剂处理的组织块显示出染色摄取增加,这表明磷脂不是髓鞘染色中该染料的主要底物。因此,该染料可用于定量组织切片中的髓磷脂。

相似文献

1
Quantitative histochemistry of myelin using Luxol Fast Blue MBS.使用卢戈氏坚牢蓝MBS进行髓鞘的定量组织化学分析。
Histochem J. 1977 Nov;9(6):759-65. doi: 10.1007/BF01003070.
2
The staining of the myelin sheath by luxol dye techniques.用卢氏染色技术对髓鞘进行染色。
J Neuropathol Exp Neurol. 1973 Apr;32(2):271-83. doi: 10.1097/00005072-197304000-00007.
3
Luxol fast blue ARN: a new solvent azo dye with improved staining qualities for myelin and phospholipids.
Stain Technol. 1962 Sep;37:313-6. doi: 10.3109/10520296209114492.
4
Rapid staining of myelin in paraffin sections with luxol fast blud MBS.用卢氏固蓝MBS对石蜡切片中的髓磷脂进行快速染色。
J Med Lab Technol. 1969 Jul;26(3):231-2.
5
LUXOL FAST BLUE G AS A MYELIN STAIN.卢氏固蓝G作为一种髓磷脂染色剂。
Stain Technol. 1964 Mar;39:123.
6
Luxol Fast Blue MBSN-Levafix Red Violet E-2BL. A combined stain for myelin sheaths and glia fibers.卢氏固蓝MBSN-丽华固红紫E-2BL。一种用于髓鞘和神经胶质纤维的联合染色剂。
Arch Pathol. 1975 Oct;99(10):529-32.
7
Certification procedures used by the Biological Stain Commission for eriochrome cyanine R (C.I. 43820, Mordant blue 3).生物染色委员会用于碱性媒介蓝 3(C.I. 43820,媒染蓝 3)的认证程序。
Biotech Histochem. 2020 Jul;95(5):396-402. doi: 10.1080/10520295.2020.1748229. Epub 2020 Apr 23.
8
TWO NEUROLOGICAL STAINING TECHNIQUES UTILIZING THE DYE LUXOL FAST BLUE.两种使用卢戈氏坚牢蓝染料的神经染色技术。
Can J Med Technol. 1965 Aug;27:118-23.
9
New applications of the Luxol fast blue myelin stain.卢氏快蓝髓磷脂染色的新应用。
Lab Invest. 1956 Nov-Dec;5(6):459-74.
10
Histochemistry of myelin XIV. Peripheral nerve myelin proteins: electrophoretic and histochemical correlations.髓鞘的组织化学十四。周围神经髓鞘蛋白:电泳与组织化学的相关性。
J Neurochem. 1972 Aug;19(8):1931-5. doi: 10.1111/j.1471-4159.1972.tb01481.x.

引用本文的文献

1
Validation of qMT and CEST MRI as Biomarkers of Response to Treatment After Lumbar Spinal Cord Injury in Rats.qMT和CEST MRI作为大鼠腰段脊髓损伤后治疗反应生物标志物的验证
NMR Biomed. 2025 Apr;38(4):e70015. doi: 10.1002/nbm.70015.
2
How to Use the Cuprizone Model to Study De- and Remyelination.如何使用杯状胶模型研究脱髓鞘和髓鞘再生。
Int J Mol Sci. 2024 Jan 24;25(3):1445. doi: 10.3390/ijms25031445.
3
Interpretable deep learning of myelin histopathology in age-related cognitive impairment.可解释的深度学习在年龄相关认知障碍中的髓鞘组织病理学研究

本文引用的文献

1
Luxol fast blue ARN: a new solvent azo dye with improved staining qualities for myelin and phospholipids.
Stain Technol. 1962 Sep;37:313-6. doi: 10.3109/10520296209114492.
2
LUXOL FAST BLUE G AS A MYELIN STAIN.卢氏固蓝G作为一种髓磷脂染色剂。
Stain Technol. 1964 Mar;39:123.
3
A method for the combined staining of cells and fibers in the nervous system.一种用于神经系统中细胞和纤维联合染色的方法。
J Neuropathol Exp Neurol. 1953 Oct;12(4):400-3. doi: 10.1097/00005072-195312040-00008.
Acta Neuropathol Commun. 2022 Sep 21;10(1):131. doi: 10.1186/s40478-022-01425-5.
4
Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment.人诱导的神经和间充质干细胞治疗联合姜黄素纳米缀合物作为脊髓损伤的治疗方法。
Int J Mol Sci. 2021 May 31;22(11):5966. doi: 10.3390/ijms22115966.
5
Abnormal social behavior in mice with tyrosinemia type I is associated with an increase of myelin in the cerebral cortex.I 型酪氨酸血症小鼠的异常社会行为与大脑皮层髓鞘增加有关。
Metab Brain Dis. 2017 Dec;32(6):1829-1841. doi: 10.1007/s11011-017-0071-8. Epub 2017 Jul 15.
6
Histological-MRI correlation in the primary motor cortex of patients with amyotrophic lateral sclerosis.肌萎缩侧索硬化症患者初级运动皮层的组织学与磁共振成像相关性研究
J Magn Reson Imaging. 2015 Mar;41(3):665-75. doi: 10.1002/jmri.24582. Epub 2014 Feb 26.
7
Neuroimaging evidence of altered fronto-cortical and striatal function after prolonged cocaine self-administration in the rat.长期可卡因自我给药后大鼠额皮质和纹状体功能改变的神经影像学证据。
Neuropsychopharmacology. 2011 Nov;36(12):2431-40. doi: 10.1038/npp.2011.129. Epub 2011 Jul 20.
8
Target-specific contrast agents for magnetic resonance microscopy.用于磁共振显微镜检查的靶向特异性造影剂。
Neuroimage. 2009 Jun;46(2):382-93. doi: 10.1016/j.neuroimage.2009.01.030.
9
Presenilin-1 mutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice.早老素-1突变使少突胶质细胞对谷氨酸和淀粉样蛋白毒性敏感,并加剧小鼠的白质损伤和记忆障碍。
Neuromolecular Med. 2003;3(1):53-64. doi: 10.1385/NMM:3:1:53.
10
Loss of intracortical myelinated fibers: a distinctive age-related alteration in the human striate area.皮质内有髓纤维的丧失:人类纹状区一种与年龄相关的独特改变。
Acta Neuropathol. 1983;61(3-4):178-82. doi: 10.1007/BF00691983.
4
Surface uptake of the azo dye Luxol ARN by human platelets.偶氮染料卢索尔ARN被人血小板的表面摄取。
Can J Biochem. 1966 Feb;44(2):161-70. doi: 10.1139/o66-020.
5
A new approach to the determination of thickness of biological specimens by two wavelength method using interference microscopy.一种使用干涉显微镜通过双波长法测定生物样本厚度的新方法。
Acta Histochem. 1967;26(1):131-43.
6
The binding of luxol fast blue ARN by various biological lipids.不同生物脂质对卢戈氏坚牢蓝ARN的结合作用。
Stain Technol. 1970 Jul;45(4):155-60. doi: 10.3109/10520297009067471.
7
The staining of the myelin sheath by luxol dye techniques.用卢氏染色技术对髓鞘进行染色。
J Neuropathol Exp Neurol. 1973 Apr;32(2):271-83. doi: 10.1097/00005072-197304000-00007.
8
Polyploidy in the human nervous system. 1. The DNA content of neurones and glia of the cerebellum.人类神经系统中的多倍体。1. 小脑神经元和神经胶质细胞的DNA含量。
J Neurol Sci. 1973 Feb;18(2):183-96. doi: 10.1016/0022-510x(73)90005-1.