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Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and alpha-keto-gamma-methiolbutyrate.

作者信息

Cooper A J

出版信息

Anal Biochem. 1978 Sep;89(2):451-60. doi: 10.1016/0003-2697(78)90374-3.

DOI:10.1016/0003-2697(78)90374-3
PMID:727444
Abstract
摘要

相似文献

1
Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and alpha-keto-gamma-methiolbutyrate.从大鼠肾脏中纯化可溶性和线粒体谷氨酰胺转氨酶K。使用一种涉及L-苯丙氨酸与α-酮-γ-甲硫基丁酸之间转氨作用的灵敏检测方法。
Anal Biochem. 1978 Sep;89(2):451-60. doi: 10.1016/0003-2697(78)90374-3.
2
A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.从大鼠肾细胞溶质中纯化得到的半胱氨酸共轭β-裂合酶。活性需要α-酮酸或氨基酸氧化酶,且与可溶性谷氨酰胺转氨酶K相同。
J Biol Chem. 1986 Nov 25;261(33):15529-37.
3
The role of mitochondrial matrix enzymes in the metabolism and toxicity of cysteine conjugates.线粒体基质酶在半胱氨酸共轭物代谢及毒性中的作用。
J Biol Chem. 1988 Mar 5;263(7):3395-401.
4
Glutamine transaminase K and cysteine S-conjugate beta-lyase activity stains.谷氨酰胺转氨酶K和半胱氨酸S-共轭β-裂合酶活性染色。
Anal Biochem. 1991 Sep 2;197(2):421-7. doi: 10.1016/0003-2697(91)90414-o.
5
Isolation and properties of a new glutamine transaminase from rat kidney.
J Biol Chem. 1974 Apr 25;249(8):2554-61.
6
High activities of glutamine transaminase K (dichlorovinylcysteine beta-lyase) and omega-amidase in the choroid plexus of rat brain.大鼠脑脉络丛中谷氨酰胺转氨酶K(二氯乙烯基半胱氨酸β-裂解酶)和ω-酰胺酶的高活性。
J Neurochem. 1993 Nov;61(5):1731-41. doi: 10.1111/j.1471-4159.1993.tb09810.x.
7
Glutamine transaminase K is not a major cysteine S-conjugate beta-lyase of rat kidney mitochondria: evidence that a high-molecular weight enzyme fulfills this role.谷氨酰胺转氨酶K不是大鼠肾线粒体的主要半胱氨酸S-共轭β-裂解酶:有证据表明一种高分子量酶发挥此作用。
Mol Pharmacol. 1995 Nov;48(5):855-60.
8
Isolation from rat kidney of a cytosolic high molecular weight cysteine-S-conjugate beta-lyase with activity toward leukotriene E4.从大鼠肾脏中分离出一种对白三烯E4有活性的胞质高分子量半胱氨酸-S-共轭β-裂解酶。
J Biol Chem. 1995 Jan 6;270(1):180-8. doi: 10.1074/jbc.270.1.180.
9
The role of transamination in methionine oxidation in the rat.转氨作用在大鼠蛋氨酸氧化中的作用。
J Nutr. 1978 Jan;108(1):67-78. doi: 10.1093/jn/108.1.67.
10
Cysteine conjugate beta-lyase of rat kidney cytosol: characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity.大鼠肾细胞质中的半胱氨酸共轭β-裂解酶:特性、免疫细胞化学定位及其与六氯丁二烯肾毒性的关系。
Toxicol Appl Pharmacol. 1989 Apr;98(2):185-97. doi: 10.1016/0041-008x(89)90224-x.

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犬尿氨酸转氨酶3/谷氨酰胺转氨酶L/半胱氨酸共轭β-裂解酶2是小鼠肾脏中的一种主要谷氨酰胺转氨酶。
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Metabolism of cisplatin to a nephrotoxin.顺铂代谢为肾毒素。
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L-methionine-dl-sulfoxide metabolism and toxicity in freshly isolated mouse hepatocytes: gender differences and inhibition with aminooxyacetic acid.L-蛋氨酸-dl-亚砜在新鲜分离的小鼠肝细胞中的代谢与毒性:性别差异及氨基氧乙酸的抑制作用
Drug Metab Dispos. 2008 Nov;36(11):2252-60. doi: 10.1124/dmd.108.023390. Epub 2008 Aug 7.
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Metabolism of the cysteine S-conjugate of busulfan involves a beta-lyase reaction.白消安的半胱氨酸S-共轭物的代谢涉及β-裂解酶反应。
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Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate beta-lyase.人谷氨酰胺转氨酶K作为转氨酶和半胱氨酸S-共轭β-裂解酶的底物特异性。
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Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells.顺铂诱导的毒性与体内小鼠肾线粒体中的铂沉积以及LLC - PK1细胞中α-酮戊二酸脱氢酶复合体的选择性失活有关。
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Plant Physiol. 1997 Dec;115(4):1541-1548. doi: 10.1104/pp.115.4.1541.