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[炎症性胰腺疾病的新进展]

[New aspects of inflammatory pancreatic diseases].

作者信息

Hotz J

出版信息

Fortschr Med. 1981 Feb 26;99(8):253-7.

PMID:7274968
Abstract

The diagnostic aids of acute pancreatitis include the clinical presentation, laboratory investigations and abdominal sonography. The assessment of amylase creatinin clearance ratio is not superior to simple amylase estimations in identifying unspecific hyperamylasemias apart from acute pancreatitis. The management of acute pancreatitis consists of a standardized basic treatment which does not depend on the degree of the severity of the disease and supplementary measures which are adjusted to the degree of severity and complications. In case of chronic pancreatitis a variety of indirect and direct morphological and functional examinations are available. The diagnostic safety of all procedures--each taken by its own--is below 90%; however, the combined use has to be adjusted to the severity of the symptoms suspicious of pancreatis disease. The therapeutic goal includes the conservative management of the painful recurrences to achieve transmission into the final stage of the disease which presents only minor symptoms. Operation has to be considered in case of untreatable pain and local complications. The obstruction of the pancreatic duct by means of synthetic glue instillations is a hopeful approach.

摘要

急性胰腺炎的诊断辅助手段包括临床表现、实验室检查和腹部超声检查。在识别除急性胰腺炎之外的非特异性高淀粉酶血症方面,淀粉酶肌酐清除率的评估并不优于简单的淀粉酶测定。急性胰腺炎的治疗包括不依赖疾病严重程度的标准化基础治疗以及根据严重程度和并发症进行调整的补充措施。对于慢性胰腺炎,有多种间接和直接的形态学及功能检查方法。所有这些检查方法单独使用时的诊断安全性均低于90%;然而,联合使用必须根据疑似胰腺疾病症状的严重程度进行调整。治疗目标包括对疼痛复发进行保守处理,以使其进入仅表现轻微症状的疾病终末期。对于无法治疗的疼痛和局部并发症,必须考虑手术治疗。通过注入合成胶水来阻塞胰管是一种有前景的方法。

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