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西非矮山羊的葡萄糖耐量

The glucose tolerance of the West African dwarf goats.

作者信息

Nair S G, Shetty S N

出版信息

Indian J Physiol Pharmacol. 1981 Jan-Mar;25(1):11-6.

PMID:7275260
Abstract

Glucose tolerance tests conducted on 4 adult goats and 3 kids, injecting glucose intravenously (0.5 g/kg body weight), showed that the former required 180 min and the latter 45 min after injection, to restore blood glucose to normal. For the adult goats, the turnover rate (K) was 0.38 +/- 0.03/hr, turnover time (TT) 2.64 +/- 0.18 hr and half-time (T 1/2) 110.24 +/- 7.73 min for glucose clearance while for the kids, these were 1.59 +/- 0.12/hr, 0.64 +/- 0.04 hr and 26.05 +/- 4.36 min respectively. The higher glucose clearance in the kids than in the adults may be attributed to a more efficient insulin response and to greater glucose utilization than in the former. The dwarf goats appear to differ substantially from the cows in their homeostatic responses to induced hyperglycemia.

摘要

对4只成年山羊和3只幼羊进行了葡萄糖耐量试验,通过静脉注射葡萄糖(0.5克/千克体重),结果显示,成年山羊在注射后需要180分钟,幼羊需要45分钟才能使血糖恢复正常。对于成年山羊,葡萄糖清除的周转率(K)为0.38±0.03/小时,周转时间(TT)为2.64±0.18小时,半衰期(T 1/2)为110.24±7.73分钟;而对于幼羊,这些数值分别为1.59±0.12/小时、0.64±0.04小时和26.05±4.36分钟。幼羊比成年山羊具有更高的葡萄糖清除率,这可能归因于幼羊比成年山羊具有更有效的胰岛素反应和更高的葡萄糖利用率。矮山羊在对诱导性高血糖的稳态反应方面似乎与奶牛有很大不同。

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