Jennings S, Cass A J, Heather B P, Greenhalgh R M
J Cardiovasc Surg (Torino). 1981 Jul-Aug;22(4):327-9.
Nineteen patients undergoing aortic surgery during which 5,000 units of heparin were given intravenously were compared with 39 patients undergoing laparotomy or herniorrhaphy. There was an expected significant reduction in coagulability as measured by thrombelastography in those patients undergoing aortic surgery. Moreover, the early post-operative deep vein thrombosis (DVT) rate was significantly less. This implies that a reduction in coagulability by I.V. heparin during surgery is associated with a lower incidence of early post-operative deep vein thrombosis. Among the laparotomy and hernia group who developed a DVT, coagulability was significantly greater both before and during the operation and on the first post-operative day.
19名接受主动脉手术的患者术中静脉注射了5000单位肝素，并与39名接受剖腹手术或疝修补术的患者进行了比较。通过血栓弹力图测量，接受主动脉手术的患者的凝血能力出现了预期的显著下降。此外，术后早期深静脉血栓形成（DVT）率显著降低。这意味着手术期间静脉注射肝素导致的凝血能力下降与术后早期深静脉血栓形成的发生率较低有关。在发生深静脉血栓的剖腹手术和疝气组中，手术前、手术期间及术后第一天的凝血能力均显著增强。
