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应用皮质酮衍生物治疗某些与尿17-酮类固醇异常升高相关的不育症病例(作者译)

[The treatment of certain cases of sterility of infertility associated with an abnormal rise in urinary 17-ketosteroids by using cortisone derivatives (author's transl)].

作者信息

Colette C, Maillet R, Gautier C, Agnani G, Guinchard B

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1981;10(2):163-9.

PMID:7276470
Abstract

45 women who were infertile with primary or secondary infertility were studied. The only abnormality that was found was biological, and it was a 24-hour excretion of urinary 17-ketosteroids higher than 35 micromoles. Treatment with cortisone derivatives resulted in 56 pregnancies, which were studied to their term whether it was abortion or delivery. The theoretical and practical aspects, as well as the diagnoses and treatments, are discussed.

摘要

对45名原发性或继发性不孕的女性进行了研究。发现的唯一异常是生物学上的,即24小时尿17-酮类固醇排泄量高于35微摩尔。用皮质类固醇衍生物治疗后有56例妊娠,对这些妊娠进行了足月研究,无论其结局是流产还是分娩。文中讨论了理论和实践方面,以及诊断和治疗方法。

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