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尿液与膀胱冲洗液对膀胱癌患者的诊断价值。

The diagnostic value of urine versus bladder washing in patients with bladder cancer.

作者信息

Murphy W M, Crabtree W N, Jukkola A F, Soloway M S

出版信息

J Urol. 1981 Sep;126(3):320-2. doi: 10.1016/s0022-5347(17)54505-x.

DOI:10.1016/s0022-5347(17)54505-x
PMID:7277589
Abstract

In a prospective, critical appraisal of simultaneously collected cystoscopic urine and bladder cancer washing for the evaluation of patients with bladder cancer little consistent difference in cellular yield or preservation could be documented between the 2 techniques. Diagnostic cells usually occurred in both types of specimens but in 20 to 30 per cent of the cases they could be identified only in cystoscopic urine. Over-all, 13.1 per cent of the cancers would have been missed had cystoscopic urine not been examined cytologically. Although bladder washing alone has a greater diagnostic yield than cystoscopic urine alone urine remains a valuable source of diagnostic information and should be evaluated, even when simultaneously collected bladder washings are available.

摘要

在一项对同时收集的膀胱镜检查尿液和膀胱癌冲洗液进行前瞻性批判性评估以评价膀胱癌患者的研究中,两种技术在细胞产量或保存方面几乎没有一致的差异。诊断性细胞通常在两种标本中都出现,但在20%至30%的病例中,仅在膀胱镜检查尿液中才能识别到。总体而言,如果未对膀胱镜检查尿液进行细胞学检查,13.1%的癌症将会漏诊。尽管单独的膀胱冲洗液比单独的膀胱镜检查尿液具有更高的诊断率,但尿液仍然是诊断信息的重要来源,即使有同时收集的膀胱冲洗液,也应对尿液进行评估。

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Urine biomarkers in bladder cancer - current status and future perspectives.膀胱癌中的尿液生物标志物——现状与未来展望
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Adequacy of urine cytology specimens: an assessment of collection techniques.
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Can cytomorphometry replace histomorphometry for grading of bladder tumours?细胞形态计量学能否取代组织形态计量学用于膀胱肿瘤分级?
Virchows Arch A Pathol Anat Histopathol. 1988;413(3):249-55. doi: 10.1007/BF00718617.