Alonso Carrasco T, Pujol Colomer J, Ayuso Gatell A, Pujol Colomer J
Med Clin (Barc). 1981 Jul 15;77(3):118-20.
Some inflammatory processes of the 9th cranial nerve may provoke disturbances of the autonomic nervous system, with parasympathetic irritation. A unilateral intracranial lesion or section of the glossopharyngeus may produce adverse reactions such as sinus tachycardia and transitory hypertension, due to a cut-off in physiological feedback. The two cases presented developed acute hypertension after either lesion or section of the 9th cranial nerve. In one case the hypertension was of a few days duration only, while the second was rather unusual in that it was sustained over a four-month period. The physiopathologic mechanisms are described as well as the favorable response to treatment with drugs. The hypothesis that arterial hypertension is caused by an over-stimulation of the beta-adrenergic system, in particular in its effect on cardiac output is, at least in part, supported by the favorable response to propranolol. In order to either confirm or discard this hypothesis, the measurement of cardiac output in successive patients after lesion or section of the glossopharyngeus is considered to be of special interest.
第九对脑神经的一些炎症过程可能会引发自主神经系统紊乱，并伴有副交感神经刺激。单侧颅内病变或舌咽神经切断可能会产生诸如窦性心动过速和短暂性高血压等不良反应，这是由于生理反馈中断所致。所呈现的这两例病例在第九对脑神经发生病变或切断后均出现了急性高血压。其中一例高血压仅持续了几天，而另一例则相当不寻常，持续了四个月。文中描述了其病理生理机制以及药物治疗的良好反应。动脉高血压是由β-肾上腺素能系统过度刺激引起的这一假说，尤其是其对心输出量的影响，至少在一定程度上得到了普萘洛尔良好反应的支持。为了证实或摒弃这一假说，对舌咽神经病变或切断后的连续患者的心输出量进行测量被认为具有特殊意义。
