Teasdale F
Placenta. 1981 Jul-Sep;2(3):241-51. doi: 10.1016/s0143-4004(81)80007-0.
Different morphometric parameters have been applied to the study of the morphological differences between a group of normal placentae and a group of placentae collected from Class A diabetic women. It has shown that although fetal weights were significantly higher in the infants of the diabetic mothers, placental weights showed only a tendency to be heavier than the gestationally matched controls, though the difference was not statistically significant. However, the placentae of the Class A diabetic mothers were shown to differ from the control group by having significantly more parenchymal and villous tissues and a higher cellular content. There were also more surface areas of exchange between mother and fetus, in terms of peripheral and villous capillary surface areas and intervillous space volume. On a functional basis, these morphological changes suggest that, in diabetes mellitus Class A, the placenta can efficiently support the growth of a large fetus, and the perinatal associated with this condition is not likely to be related to decreased or insufficient function of the placenta.
不同的形态测量参数已被应用于研究一组正常胎盘与一组从 A 类糖尿病女性收集的胎盘之间的形态差异。结果表明，虽然糖尿病母亲的婴儿出生体重显著更高，但胎盘重量仅显示出比孕周匹配的对照组更重的趋势，尽管差异无统计学意义。然而，A 类糖尿病母亲的胎盘与对照组相比，实质和绒毛组织明显更多，细胞含量更高。从周边和绒毛毛细血管表面积以及绒毛间隙体积来看，母婴之间的交换表面积也更大。从功能角度来看，这些形态学变化表明，在 A 类糖尿病中，胎盘能够有效地支持巨大胎儿的生长，并且与这种情况相关的围产期情况不太可能与胎盘功能下降或不足有关。
