Gondos B
Prog Clin Biol Res. 1981;59B:373-81.
Information on the cellular changes involved in human gonadal maturation has increased considerably in recent years with the introduction of special techniques for coordinating structural and functional analyses. An approach that appears to be particularly promising is the use of freeze-fracture techniques. Utilizing this method, we have demonstrated the formation of specialized intercellular junctions in the developing ovary and testis. Studies in several species have indicated similar findings which relate to the formation of the blood-testis barrier and the coordination of cellular activity involved in steroidogenesis. Further progress in understanding of maturational changes in the developing gonads will depend on continuing correlation of structural and functional changes in specific cell populations.
近年来，随着用于协调结构和功能分析的特殊技术的引入，有关人类性腺成熟过程中细胞变化的信息大幅增加。一种似乎特别有前景的方法是使用冷冻断裂技术。利用这种方法，我们已经证明了在发育中的卵巢和睾丸中形成了特殊的细胞间连接。对几个物种的研究表明了类似的发现，这些发现与血睾屏障的形成以及类固醇生成过程中细胞活动的协调有关。在理解发育中性腺成熟变化方面的进一步进展将取决于特定细胞群体中结构和功能变化的持续关联。
