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计算机断层扫描在膀胱癌和前列腺癌的评估、分期及治疗中的应用

Computed tomography in the evaluation, staging, and therapy of carcinoma of the bladder and prostate.

作者信息

Morgan C L, Calkins R F, Cavalcanti E J

出版信息

Radiology. 1981 Sep;140(3):751-61. doi: 10.1148/radiology.140.3.7280246.

DOI:10.1148/radiology.140.3.7280246
PMID:7280246
Abstract

Computed tomography was performed in 24 patients with bladder carcinoma, 29 patients with prostate carcinoma, and one patient with simultaneous bladder and prostate carcinoma. In nine patients (16%), the stage of the carcinoma would have been underestimated based on CT alone. Six of these nine patients had only microscopic or laboratory evidence (elevated serum acid phosphatase level) of more widespread disease than what was demonstrated by CT. The overall accuracy of pelvic lymph node evaluation by CT was 79% in 34 patients. The 21% inaccuracy arises from five false-negative cass in which there was microscopic involvement within normal-sized nodes (4 patients) or only minimally enlarged (2.0 cm or less) nodes (1 patient), and two false-positive cases related to benign changes in nodes. CT was unable to differentiate Stage A, B1, and B2 bladder tumors. CT was used in planning portals for 16 patients who underwent external beam radiation therapy. CT was also used to measure the volume of the prostate prior to placement of 125I seeds for therapy, and to assess the positioning of the seeds.

摘要

对24例膀胱癌患者、29例前列腺癌患者以及1例同时患有膀胱癌和前列腺癌的患者进行了计算机断层扫描。在9例患者(16%)中,仅基于CT会低估癌症分期。这9例患者中有6例仅有比CT显示的更广泛疾病的微观或实验室证据(血清酸性磷酸酶水平升高)。在34例患者中,CT评估盆腔淋巴结的总体准确率为79%。21%的不准确情况源于5例假阴性病例,其中正常大小的淋巴结内有微观累及(4例患者)或仅有轻度肿大(2.0厘米或更小)的淋巴结(1例患者),以及2例假阳性病例与淋巴结的良性改变有关。CT无法区分A期、B1期和B2期膀胱肿瘤。CT用于为16例接受外照射放疗的患者规划照射野。在植入125I种子进行治疗前,CT还用于测量前列腺体积,并评估种子的定位。

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