Lygidakis N J
Surg Gynecol Obstet. 1981 Oct;153(4):532-6.
To assess the role of extrahepatic biliary obstruction in the production of damage to the liver and biliary ductal apparatus, 100 patients underwent choledochoduodenostomy for malignant or benign extrahepatic biliary obstruction. Patients were observed by means of barium meal studies for one month to one year postoperatively. Emphasis was placed upon the relationship of the appearance, structure and function of the extrahepatic and intrahepatic biliary tree in these studies with the findings after histologic examination of the liver, gallbladder or commmon bile duct wall; liver function tests, and cultures of the bile. It has been shown that barium meal studies are an indicative criterion for the evaluation of the extent and progress of the hepatobiliary damage and of its further development after relief of the obstruction. It has been proved that chronic extrahepatic biliary obstruction of long standing seen in patients with a long history of symptoms, with a high incidence of primary common bile duct stones and with a high rate of contaminated bile as well as a high percentage of common bile duct dilation is a challenging and serious disease for both the patient and the hepatobiliary apparatus.
为评估肝外胆管梗阻在肝及胆管系统损害形成中的作用，对100例因恶性或良性肝外胆管梗阻而行胆总管十二指肠吻合术的患者进行了研究。术后通过钡餐检查对患者进行了1个月至1年的观察。这些研究重点关注肝外和肝内胆管树的外观、结构和功能与肝脏、胆囊或胆总管壁组织学检查结果、肝功能测试及胆汁培养结果之间的关系。结果表明，钡餐检查是评估肝胆损害程度、进展情况及其梗阻解除后进一步发展的一项指示性标准。已证实，对于有长期症状史、原发性胆总管结石发生率高、胆汁污染率高以及胆总管扩张比例高的患者中所见的长期慢性肝外胆管梗阻，对患者和肝胆系统来说都是一种具有挑战性的严重疾病。
