Kostandov E A, Arzumanov Iu L, Genkina O A, Reshchikova T N, Shostakovich G S
Zh Vyssh Nerv Deiat Im I P Pavlova. 1981 May-Jun;31(3):451-63.
By means of backward masking, the time of perception of letter stimuli presented to the left and right visual fields, was determined in practically healthy persons who were given different doses of alcohol, and in patients with chronic alcoholism. Evoked electrical activity to the same stimuli was recorded in identical conditions. A small dose of alcohol (0.41 g/kg) increases in healthy subjects the time of perception of visual signals only if they are presented in the left visual field: a medium dose (0.82 g/kg) increases the time of stimuli perception in both halves of the visual field, but obviously more so in the left one, in patients with chronic alcoholism the time of perception is substantially longer in the left visual field. A small dose of alcohol does not affect evoked electrical cortical activity in healthy persons. Distinct regional differences are exhibited in the action of the medium dose of alcohol on the cerebral cortex of healthy persons. Evoked potential in the central area is depressed to a greater extent than in the visual and associative (Brodman field 37) zones. With chronic alcohol intoxication, evoked activity in the right hemisphere is depressed considerably more than in the left one.
通过逆向掩蔽法，测定了给予不同剂量酒精的实际健康者以及慢性酒精中毒患者对呈现于左、右视野的字母刺激的感知时间。在相同条件下记录对相同刺激的诱发电活动。小剂量酒精（0.41克/千克）仅在视觉信号呈现于左视野时才会增加健康受试者对其的感知时间；中等剂量（0.82克/千克）会增加视野两侧刺激的感知时间，但在左视野更为明显，慢性酒精中毒患者左视野的感知时间明显更长。小剂量酒精对健康人的诱发性皮层电活动无影响。中等剂量酒精对健康人大脑皮层的作用表现出明显的区域差异。中央区的诱发电位比视觉区和联合区（布罗德曼37区）受到的抑制程度更大。慢性酒精中毒时，右半球的诱发电活动比左半球受到的抑制程度明显更大。
