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儿童颅内动静脉畸形。25例病例回顾(作者译)

[Intracranial arteriovenous malformations in childhood. A revision of 25 cases (author's transl)].

作者信息

Narbona J, Lyon G

出版信息

An Esp Pediatr. 1981 Apr;14(4):226-32.

PMID:7283283
Abstract

Clinical features of A-V intracranial malformations during infancy, childhood and adolescence are reviewed on this series of 25 less-than-15-years-old patients. Great cirsoid malformations (2 cases) and aneurysms of the vein of Galen (2 cases) may cause diffuse brain-steal-ischaemia, hydrocephalus and congestive heart failure in early ages, event at birth. The clinical manifestations of brain angiomas rather begin from the fifth year of life. Little sized angiomas cause preferentially intracranial haemorrhagic attacks (17 of 21 cases in this series). Middle sized racemic angiomas cause focal seizures and/or focal neurologic signs. In 5 patients an intracranial bruit of a great diagnostic value was present. Combining brain radioisotopic studies, brain C.A.T. and angiography near 100% of intracranial A-V malformations can be diagnosed early after clinical suspicion.

摘要

本文回顾了25例15岁以下患者的婴幼儿期、儿童期和青少年期动静脉颅内畸形的临床特征。巨大海绵状畸形(2例)和大脑大静脉瘤(2例)在早期,甚至在出生时,就可能导致弥漫性脑盗血缺血、脑积水和充血性心力衰竭。脑血管瘤的临床表现通常从生命的第五年开始。小尺寸的血管瘤优先导致颅内出血发作(本系列21例中有17例)。中等尺寸的双侧血管瘤导致局灶性癫痫发作和/或局灶性神经体征。5例患者出现具有重大诊断价值的颅内杂音。结合脑放射性同位素研究、脑CT和血管造影,在临床怀疑后近100%的颅内动静脉畸形可早期诊断。

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