二硝基氯苯（DNCB）皮肤超敏反应与DNCB包被的人红细胞对白细胞迁移的抑制作用之间的相关性。

Correlations between DNCB skin hypersensitivity and leukocyte migration inhibition by DNCB-coated human erythrocytes.

作者信息

Walewski J, Nowakowska A

出版信息

Arch Immunol Ther Exp (Warsz). 1981;29(1):29-33.

Abstract

Correlations between skin hypersensitivity to DNCB and LMI in presence of lyophilized, DNCB-coated human erythrocytes were evaluated. False positive results were found in 2 out of 25 (8%) non-sensitized donors and false negative--in 5 out of 21 (24%) sensitized patients. In follow-up evaluation after topical DNCB sensitization significant MI was usually seen about 3 weeks after sensitization and only in a part of patients after 6-9 weeks. Time limitations in the application of LMI test for evaluation of effects of immunosuppressive treatment are discussed.

摘要

评估了在存在冻干的、包被二硝基氯苯（DNCB）的人红细胞的情况下，皮肤对DNCB的超敏反应与淋巴细胞迁移抑制指数（LMI）之间的相关性。在25名未致敏供者中有2名（8%）出现假阳性结果，在21名致敏患者中有5名（24%）出现假阴性结果。在局部DNCB致敏后的随访评估中，显著的迁移抑制通常在致敏后约3周出现，只有部分患者在6 - 9周后出现。讨论了LMI试验在评估免疫抑制治疗效果应用中的时间限制。