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中脑网状结构在内脏影响习惯化形成过程中的参与作用。

Participation of the reticular formation of the mesencephalon in the development of habituation to visceral influences.

作者信息

Chernigovskii V N, Musyashchikova S S, Mokrushin A A, Sinyaya M S

出版信息

Biol Bull Acad Sci USSR. 1981 Jan-Feb;8(1):14-20.

PMID:7284475
Abstract

In experiments on cats anesthetized with chloralose and immobilized with flaxedil, the influence of the reticular formation (RF) of the mesencephalon on the development of habituation of evoked potentials (EP) in the cerebral cortex (CC) to repeated stimulation of the splanchnic nerve was studied. It was established that high frequency stimulation of the RF (100 counts/sec) for 15 sec before testing for habituation to visceral stimulation inhibited the amplitude of the EP and shortened the time of development of habituation to repeated stimulation of the splanchnic nerve. Low-frequency stimulation of the RF (1 pulse/sec), applied during the development of habituation, restored the amplitude of the EP to the initial level. The turnoff of the activity of the RF by intravenously injected chlorpromazine (3-6 mg/kg) was accompanied by an acceleration of the development of habituation of evoked potentials in the associative region of the cortex. The participation of the RF in processes of habituation and dehabituation is discussed.

摘要

在用氯醛糖麻醉并用三碘季铵酚固定的猫的实验中,研究了中脑网状结构(RF)对大脑皮层(CC)中诱发电位(EP)对反复刺激内脏神经的习惯化发展的影响。已确定,在测试对内脏刺激的习惯化之前,以100次/秒的高频刺激RF 15秒会抑制EP的幅度,并缩短对反复刺激内脏神经的习惯化发展时间。在习惯化发展过程中施加的RF低频刺激(1次脉冲/秒)可使EP的幅度恢复到初始水平。静脉注射氯丙嗪(3 - 6毫克/千克)使RF的活动停止,同时伴随着皮层联合区域诱发电位习惯化发展的加速。文中讨论了RF在习惯化和去习惯化过程中的参与情况。

相似文献

1
Participation of the reticular formation of the mesencephalon in the development of habituation to visceral influences.中脑网状结构在内脏影响习惯化形成过程中的参与作用。
Biol Bull Acad Sci USSR. 1981 Jan-Feb;8(1):14-20.
2
Dynamics of habituation in different cortical regions of the cat brain.猫脑不同皮质区域的习惯化动态
Biol Bull Acad Sci USSR. 1979 Jan-Feb;6(1):1-7.
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Characteristics of habituation in visceral systems.内脏系统中的习惯化特征。
Neurosci Behav Physiol. 1981 Sep-Oct;11(5):470-7. doi: 10.1007/BF01182800.
4
[Effect of the intensity of repeated splanchnic nerve stimulation on the development of habituation in the cat cerebral cortex].[反复内脏神经刺激强度对猫大脑皮层习惯化形成的影响]
Fiziol Zh SSSR Im I M Sechenova. 1978 Nov;64(11):1521-9.
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Fiziol Zh SSSR Im I M Sechenova. 1976 Oct;62(10):1409-15.
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[Characteristics of habituation in visceral systems].[内脏系统中的习惯化特征]
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